Active Biotech Commences Clinical Phase I Combination Study of ANYARA and Taxotere®


This dose-escalation study, expected to include between 20 and 30 patients, will examine the response to increasing doses of ANYARA in combination with a fixed dose of Taxotere®. Taxotere® will be administered according to the established dosing schedule; ANYARA will be dosed at levels expected to have an anti-tumor effect.
Professor Roger Cohen of Fox Chase Cancer Center in Philadelphia, PA (USA) is the principal investigator for the trial.The study will be conducted at clinics in the USA, Denmark and Russia.
Additionally, Active Biotech is conducting a clinical Phase I dose-escalation study of ANYARA-only that is currently ongoing in the USA, Norway and the UK.
Lund 8 November, 2005
Active Biotech AB (publ)
Sven Andréasson
President & CEO
For further information, please contact:
Sven Andréasson, President & CEO, tel: +46 46-19 20 49
Tomas Leanderson, Chief Scientific Officer, tel: +46 46-19 20 95
Cecilia Hofvander, Manager Corporate Communication, tel: +46 46-19 11 22
Active Biotech AB is a biotechnology company focusing on research and development of pharmaceuticals. Active Biotech has a strong R&D portfolio with pipeline products focused on autoimmune/inflammatory diseases and cancer. Most advanced projects are laquinimod, an orally administered small molecule with unique immunomodulatory properties for the treatment of multiple sclerosis, as well as ANYARA for use in cancer immunotherapy with the primary indication non-small cell lung cancer. Further key projects in clinical development comprise the three orally administered compounds TASQ for prostate cancer 57-57 for SLE and RhuDex® for RA.
Active Biotech AB
Box 724, SE-220 07 Lund
Tel: +46 46-19 20 00
Fax: +46 46-19 20 50